Once the quest starts, the Courier can talk to the receptionist in the main entrance of Gomorrah. The Courier can also automatically receive this quest upon accepting The House Always Wins IV from Mr. She will then tell the Courier to talk to Liza O'Malley to start this quest. In For the Republic, Part 2, the Courier will be asked to get some information regarding the Omertas by Colonel Moore. Otherwise, the Courier will have to return to Yes Man and opt to ignore the Omertas, if they've given up finding clues.

If the Courier is going to do the Wild Card quests, make sure to ask him about the Omertas, so that new speech options progress the quest when exploring Gomorrah. This quest can also be activated after talking to Yes Man. He mentions that the Omertas have stopped buying guns from him without a word as to why. This quest can be given by Mick at Mick & Ralph's after asking him for work. Finally, completing this quest incorrectly prevents the player character from acquiring the Pimp-Boy 3 Billion. Also, If the Courier does not speak to Liza O'Malley before starting How Little We Know, they will not be able to complete For the Republic, Part 2 see Bugs below. It is best taken after completing Bye Bye Love, as completing this quest will render Bye Bye Love either unobtainable or unable to be completed. Warning: It is tricky to avoid permanently locking options in this quest. Detailed walkthrough (NCR/House/Yes Man)

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